| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carboxypeptidase B |
|---|
| Ligand | BDBM50201439 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_453905 (CHEMBL885909) |
|---|
| IC50 | 4650±n/a nM |
|---|
| Citation |  Islam, I; Bryant, J; May, K; Mohan, R; Yuan, S; Kent, L; Morser, J; Zhao, L; Vergona, R; White, K; Adler, M; Whitlow, M; Buckman, BO 3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg Med Chem Lett17:1349-54 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carboxypeptidase B |
|---|
| Name: | Carboxypeptidase B |
|---|
| Synonyms: | CBPB1_PIG | CPB | CPB1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47371.10 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_453905 |
|---|
| Residue: | 416 |
|---|
| Sequence: | MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQ
IKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYN
NWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREW
ISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTN
AGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAY
LTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAG
GSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
|
|
|
|---|
| BDBM50201439 |
|---|
| n/a |
|---|
| Name | BDBM50201439 |
|---|
| Synonyms: | 2-(2-chloro-5-guanidinophenyl)-3-mercaptopropanoic acid | CHEMBL245985 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H12ClN3O2S |
|---|
| Mol. Mass. | 273.739 |
|---|
| SMILES | [#7]\[#6](-[#7])=[#7]\c1ccc(Cl)c(c1)-[#6](-[#6]-[#16])-[#6](-[#8])=O |
|---|
| Structure | 
|
|---|
Search and Browse
