| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase B |
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| Ligand | BDBM50201438 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453905 (CHEMBL885909) |
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| IC50 | 10±n/a nM |
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| Citation |  Islam, I; Bryant, J; May, K; Mohan, R; Yuan, S; Kent, L; Morser, J; Zhao, L; Vergona, R; White, K; Adler, M; Whitlow, M; Buckman, BO 3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa). Bioorg Med Chem Lett17:1349-54 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase B |
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| Name: | Carboxypeptidase B |
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| Synonyms: | CBPB1_PIG | CPB | CPB1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47371.10 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_453905 |
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| Residue: | 416 |
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| Sequence: | MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQ
IKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYN
NWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREW
ISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTN
AGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAY
LTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAG
GSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
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| BDBM50201438 |
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| n/a |
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| Name | BDBM50201438 |
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| Synonyms: | (+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid | 5-guanidino-2-(mercaptomethyl)pentanoic acid | CHEMBL236822 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H15N3O2S |
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| Mol. Mass. | 205.278 |
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| SMILES | [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6](-[#6]-[#16])-[#6](-[#8])=O |
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| Structure | 
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