| Reaction Details |
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 | Report a problem with these data |
| Target | Pro-cathepsin H |
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| Ligand | BDBM50201699 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_438182 (CHEMBL907575) |
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| IC50 | >10000±n/a nM |
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| Citation |  Epple, R; Urbina, HD; Russo, R; Liu, H; Mason, D; Bursulaya, B; Tumanut, C; Li, J; Harris, JL Bicyclic carbamates as inhibitors of papain-like cathepsin proteases. Bioorg Med Chem Lett17:1254-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pro-cathepsin H |
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| Name: | Pro-cathepsin H |
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| Synonyms: | CATH_HUMAN | CBSP | CPSB | CTSH | Cathepsin H | Cathepsin H heavy chain | Cathepsin H light chain | Cathepsin H mini chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37402.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1459870 |
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| Residue: | 335 |
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| Sequence: | MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS
NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV
DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG
CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV
EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK
NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
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| BDBM50201699 |
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| n/a |
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| Name | BDBM50201699 |
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| Synonyms: | (1R,2S)-2-isobutoxy-7-oxa-5-aza-bicyclo[3.2.1]octan-6-one | CHEMBL230478 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H17NO3 |
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| Mol. Mass. | 199.2469 |
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| SMILES | CC(C)CO[C@H]1CCN2C[C@H]1OC2=O |
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| Structure | 
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