| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50202920 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_441650 (CHEMBL891881) |
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| Ki | 0.3±n/a nM |
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| Citation |  Guillon, CD; Koppel, GA; Brownstein, MJ; Chaney, MO; Ferris, CF; Lu, SF; Fabio, KM; Miller, MJ; Heindel, ND; Hunden, DC; Cooper, RD; Kaldor, SW; Skelton, JJ; Dressman, BA; Clay, MP; Steinberg, MI; Bruns, RF; Simon, NG Azetidinones as vasopressin V1a antagonists. Bioorg Med Chem15:2054-80 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM50202920 |
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| n/a |
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| Name | BDBM50202920 |
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| Synonyms: | 2(R)-[[4-(piperidin-1-yl)piperidin-1-yl]carbonylmethyl]-2-[3(S)-(4(S)-phenyloxazolidin-2-on-3-yl)-4(R)-(2-styryl)azetidin-2-on-1-yl]acetic acid N-[(R)-alpha-methylbenzyl]amide | CHEMBL395817 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H49N5O5 |
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| Mol. Mass. | 703.869 |
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| SMILES | C[C@@H](NC(=O)[C@@H](CC(=O)N1CCC(CC1)N1CCCCC1)N1[C@H](\C=C\c2ccccc2)[C@H](N2[C@H](COC2=O)c2ccccc2)C1=O)c1ccccc1 |
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| Structure | 
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