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TargetBDKRB2
LigandBDBM50203207
Substrate/Competitorn/a
Meas. Tech.ChEMBL_425212
Ki 56000±n/a nM
Citation D'Amico DCAya THuman JFotsch CChen JJBiswas KRiahi BNorman MHWilloughby CAHungate RReider PJBiddlecome GLester-Zeiner DStaden CVJohnson EKamassah AArik LWang JViswanadhan VNGroneberg RDZhan JSuzuki HToro AMareska DAClarke DEHarvey DMBurgess LELaird ERAskew BNg G Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity. J Med Chem 50:607-10 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
BDKRB2
Name:Bradykinin B2 receptor
Synonyms:B2 BRADYKININ | B2 bradykinin receptor | B2R | BK-2 receptor | Bradykinin B2 receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:44467.17
Organism:Homo sapiens (Human)
Description:B2 BRADYKININ BDKRB2 HUMAN::P30411
Residue:391
Sequence:
MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
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  Blast E-value cutoff:
BDBM50203207
n/a
NameBDBM50203207
Synonyms:3-(RS)-N-(4-(piperidin-1-ylmethyl)benzyl)-3-(naphthalene-7-sulfonamido)-3-phenylpropanamide | CHEMBL221691
TypeSmall organic molecule
Emp. Form.C32H35N3O3S
Mol. Mass.541.704
SMILESO=C(CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NCc1ccc(CN2CCCCC2)cc1
Structure
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