Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBDKRB2
LigandBDBM50203198
Substrate/Competitorn/a
Meas. Tech.ChEMBL_425212
Ki 13300±n/a nM
Citation D'Amico DCAya THuman JFotsch CChen JJBiswas KRiahi BNorman MHWilloughby CAHungate RReider PJBiddlecome GLester-Zeiner DStaden CVJohnson EKamassah AArik LWang JViswanadhan VNGroneberg RDZhan JSuzuki HToro AMareska DAClarke DEHarvey DMBurgess LELaird ERAskew BNg G Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity. J Med Chem 50:607-10 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
BDKRB2
Name:Bradykinin B2 receptor
Synonyms:B2 BRADYKININ | B2 bradykinin receptor | B2R | BK-2 receptor | Bradykinin B2 receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:44467.17
Organism:Homo sapiens (Human)
Description:B2 BRADYKININ BDKRB2 HUMAN::P30411
Residue:391
Sequence:
MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50203198
n/a
NameBDBM50203198
Synonyms:(R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((S)-5-(piperidin-1-ylmethyl)-2,3-dihydro-1H-inden-1-yl)propanamide | CHEMBL414091
TypeSmall organic molecule
Emp. Form.C34H37N3O3S
Mol. Mass.567.741
SMILESO=C(C[C@@H](NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)N[C@H]1CCc2cc(CN3CCCCC3)ccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: