| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50206172 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_454683 (CHEMBL886703) |
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| Ki | 9±n/a nM |
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| Citation |  Suckling, CJ; Murphy, JA; Khalaf, AI; Zhou, SZ; Lizos, DE; van Nhien, AN; Yasumatsu, H; McVie, A; Young, LC; McCraw, C; Waterman, PG; Morris, BJ; Pratt, JA; Harvey, AL M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds. Bioorg Med Chem Lett17:2649-55 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50206172 |
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| n/a |
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| Name | BDBM50206172 |
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| Synonyms: | 1-(benzo[d][1,3]dioxol-5-ylmethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole | 1-Benzo[1,3]dioxol-5-ylmethyl-2,3,4,9-tetrahydro-1H-beta-carboline | CHEMBL328476 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O2 |
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| Mol. Mass. | 306.3584 |
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| SMILES | C(C1NCCc2c1[nH]c1ccccc21)c1ccc2OCOc2c1 |
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| Structure | 
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