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TargetMu-type opioid receptor
LigandBDBM50206652
Substrate/Competitorn/a
Meas. Tech.ChEMBL_438449 (CHEMBL887549)
Ki 6900±n/a nM
Citation Lee, YSNyberg, JMoye, SAgnes, RSDavis, PMa, SWLai, JPorreca, FVardanyan, RHruby, VJ Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors. Bioorg Med Chem Lett17:2161-5 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44503.11
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50206652
n/a
NameBDBM50206652
Synonyms:(R)-N-(1-(2-amino-3-(4-chlorophenyl)propanoyl)piperidin-4-yl)-N-phenylpropionamide | CHEMBL231353
TypeSmall organic molecule
Emp. Form.C23H28ClN3O2
Mol. Mass.413.94
SMILESCCC(=O)N(C1CCN(CC1)C(=O)[C@H](N)Cc1ccc(Cl)cc1)c1ccccc1
Structure
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