| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
|---|
| Ligand | BDBM50207907 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_455075 (CHEMBL887104) |
|---|
| IC50 | 440±n/a nM |
|---|
| Citation |  Gross, MF; Beaudoin, S; McNaughton-Smith, G; Amato, GS; Castle, NA; Huang, C; Zou, A; Yu, W Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel. Bioorg Med Chem Lett17:2849-53 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily A member 5 |
|---|
| Name: | Potassium voltage-gated channel subfamily A member 5 |
|---|
| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67222.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22460 |
|---|
| Residue: | 613 |
|---|
| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
|
|
|
|---|
| BDBM50207907 |
|---|
| n/a |
|---|
| Name | BDBM50207907 |
|---|
| Synonyms: | CHEMBL239807 | N-((7R,8R)-8-(4-ethylphenylsulfonamido)-7-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-3-methoxybenzamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H28N2O5S |
|---|
| Mol. Mass. | 480.576 |
|---|
| SMILES | CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)CCc2ccc(NC(=O)c3cccc(OC)c3)cc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
