| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
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| Ligand | BDBM50207910 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_455075 (CHEMBL887104) |
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| IC50 | 880±n/a nM |
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| Citation |  Gross, MF; Beaudoin, S; McNaughton-Smith, G; Amato, GS; Castle, NA; Huang, C; Zou, A; Yu, W Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel. Bioorg Med Chem Lett17:2849-53 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 5 |
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| Name: | Potassium voltage-gated channel subfamily A member 5 |
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| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 67222.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22460 |
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| Residue: | 613 |
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| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
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| BDBM50207910 |
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| n/a |
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| Name | BDBM50207910 |
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| Synonyms: | CHEMBL391488 | N-((2R,3R)-3-(4-ethylphenylsulfonamido)-2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-methoxybenzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26N2O5S |
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| Mol. Mass. | 466.549 |
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| SMILES | CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)Cc2cccc(NC(=O)c3cccc(OC)c3)c12 |
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| Structure | 
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