| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50210242 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_443967 (CHEMBL892114) |
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| Ki | 37±n/a nM |
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| Citation |  Ho, GD; Bercovici, A; Tulshian, D; Greenlee, WJ; Fawzi, A; Fernandez, X; McLeod, RL; Smith Torhan, A; Zhang, H Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 2. Bioorg Med Chem Lett17:3028-33 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50210242 |
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| n/a |
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| Name | BDBM50210242 |
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| Synonyms: | 4-(2-(aminomethyl)phenyl)-1-(bis(2-fluorophenyl)methyl)piperidin-4-ol | CHEMBL233955 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H26F2N2O |
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| Mol. Mass. | 408.4835 |
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| SMILES | NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1F)c1ccccc1F |
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| Structure | 
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