Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50210556 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_444081 (CHEMBL893244) |
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Ki | 360±n/a nM |
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Citation | Peng, X; Knapp, BI; Bidlack, JM; Neumeyer, JL In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. Bioorg Med Chem15:4106-12 (2007) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50210556 |
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n/a |
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Name | BDBM50210556 |
Synonyms: | CHEMBL390912 | MCL-458 | oxazole-2-one-N-cyclobutylmethylmorphinan |
Type | Small organic molecule |
Emp. Form. | C22H28N2O2 |
Mol. Mass. | 352.4699 |
SMILES | O=c1[nH]c2cc3C[C@@H]4[C@@H]5CCCC[C@]5(CCN4CC4CCC4)c3cc2o1 |TLB:17:16:5.22.6:8| |
Structure |
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