| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor 4 |
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| Ligand | BDBM50211399 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_435005 (CHEMBL920256) |
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| Ki | 0.2±n/a nM |
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| Citation |  Vogensen, SB; Frydenvang, K; Greenwood, JR; Postorino, G; Nielsen, B; Pickering, DS; Ebert, B; Bølcho, U; Egebjerg, J; Gajhede, M; Kastrup, JS; Johansen, TN; Clausen, RP; Krogsgaard-Larsen, P A tetrazolyl-substituted subtype-selective AMPA receptor agonist. J Med Chem50:2408-14 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor 4 |
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| Name: | Glutamate receptor 4 |
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| Synonyms: | GRIA4_RAT | Glur4 | Glutamate receptor ionotropic, AMPA 4 | Glutamate receptors NMDA/AMPA | Gria4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 100766.57 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_539474 |
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| Residue: | 902 |
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| Sequence: | MRIICRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVTKLMDRWKKLDQREYPGSETPPKYTSAL
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIENRTVVVT
TIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGARDADTK
IWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL
DPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLW
FSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED
LAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKG
KFAFLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLKLNEQGL
LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKS
RAEAKRMKLTFSEATRNKARLSITGSVGENGRVLTPDCPKAVHTGTAIRQSSGLAVIASD
LP
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| BDBM50211399 |
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| n/a |
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| Name | BDBM50211399 |
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| Synonyms: | (RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid | 2-AMINO-3-[3-HYDROXY-5-(2-BENZYL-2H-5-TETRAZOLYL)-4-ISOXAZOLYL]-PROPIONIC ACID | CHEMBL388746 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N6O4 |
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| Mol. Mass. | 330.2988 |
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| SMILES | NC(Cc1c(o[nH]c1=O)-c1nnn(Cc2ccccc2)n1)C(O)=O |
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| Structure | 
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