| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50212045 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436507 (CHEMBL904813) |
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| Ki | 7.92±n/a nM |
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| Citation |  Di Giacomo, B; Bedini, A; Spadoni, G; Tarzia, G; Fraschini, F; Pannacci, M; Lucini, V Synthesis and biological activity of new melatonin dimeric derivatives. Bioorg Med Chem15:4643-50 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50212045 |
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| n/a |
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| Name | BDBM50212045 |
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| Synonyms: | 8-(3-(2-acetamidoethyl)-5-methoxy-1H-indole-2-carbonyloxy)octyl 3-(2-acetamidoethyl)-5-methoxy-1Hindole-2-carboxylate | CHEMBL387655 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H46N4O8 |
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| Mol. Mass. | 662.7724 |
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| SMILES | COc1ccc2[nH]c(C(=O)OCCCCCCCCOC(=O)c3[nH]c4ccc(OC)cc4c3CCNC(C)=O)c(CCNC(C)=O)c2c1 |
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| Structure | 
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