| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Ligand | BDBM50212163 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_455656 (CHEMBL886439) |
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| IC50 | 549±n/a nM |
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| Citation |  Vu, AT; Campbell, AN; Harris, HA; Unwalla, RJ; Manas, ES; Mewshaw, RE ERbeta ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor beta-selective ligands. Bioorg Med Chem Lett17:4053-6 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Name: | Isoform 1 of Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | Estrogen-related receptor, beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 (ERRbeta2-delta10) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56220.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_940755 |
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| Residue: | 508 |
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| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKVGQEQLRGSPKDERMSSHDGKCPFQSAAFTSRDQSNSPGIPNPRPSSP
TPLNERGRQISPSTRTPGGQGKHLWLTM
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| BDBM50212163 |
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| n/a |
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| Name | BDBM50212163 |
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| Synonyms: | 7-(4-methoxyphenyl)-6H-chromeno[4,3-b]quinoline-3,9-diol | CHEMBL250507 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H17NO4 |
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| Mol. Mass. | 371.3854 |
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| SMILES | COc1ccc(cc1)-c1c2COc3cc(O)ccc3-c2nc2ccc(O)cc12 |
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| Structure | 
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