| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid hormone receptor ERR1 |
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| Ligand | BDBM50212173 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_455655 (CHEMBL886438) |
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| IC50 | 3.6±n/a nM |
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| Citation |  Vu, AT; Campbell, AN; Harris, HA; Unwalla, RJ; Manas, ES; Mewshaw, RE ERbeta ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor beta-selective ligands. Bioorg Med Chem Lett17:4053-6 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid hormone receptor ERR1 |
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| Name: | Steroid hormone receptor ERR1 |
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| Synonyms: | ERR-alpha | ERR1 | ERR1_HUMAN | ESRL1 | ESRRA | Estrogen receptor-like 1 | Estrogen-Related Receptor, alpha | Estrogen-related receptor alpha | NR3B1 | Nuclear receptor subfamily 3 group B member 1 | Steroid hormone receptor ERR1 | Steroid hormone receptor ERR1 alpha | Steroid hormone receptor ERR1/Estrogen-related receptor alpha (ERRa) | von Hippel-Lindau disease tumor suppressor/Steroid hormone receptor ERR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45508.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1499891 |
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| Residue: | 423 |
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| Sequence: | MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
MMD
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| BDBM50212173 |
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| n/a |
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| Name | BDBM50212173 |
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| Synonyms: | 7-bromo-6H-chromeno[4,3-b]quinoline-3,9-diol | CHEMBL250097 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10BrNO3 |
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| Mol. Mass. | 344.16 |
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| SMILES | Oc1ccc-2c(OCc3c(Br)c4cc(O)ccc4nc-23)c1 |
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| Structure | 
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