| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50213120 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_436827 (CHEMBL905129) |
|---|
| Ki | 1950±n/a nM |
|---|
| Citation |  Jozwiak, K; Khalid, C; Tanga, MJ; Berzetei-Gurske, I; Jimenez, L; Kozocas, JA; Woo, A; Zhu, W; Xiao, RP; Abernethy, DR; Wainer, IW Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor. J Med Chem50:2903-15 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50213120 |
|---|
| n/a |
|---|
| Name | BDBM50213120 |
|---|
| Synonyms: | (R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylaminopropane | CHEMBL228996 | US10617654, Compound (R,S)-2 | US9249163, 33 | US9492405, (R,S)-2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H23NO4 |
|---|
| Mol. Mass. | 317.3795 |
|---|
| SMILES | COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
