| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50213118 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436827 (CHEMBL905129) |
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| Ki | 28800±n/a nM |
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| Citation |  Jozwiak, K; Khalid, C; Tanga, MJ; Berzetei-Gurske, I; Jimenez, L; Kozocas, JA; Woo, A; Zhu, W; Xiao, RP; Abernethy, DR; Wainer, IW Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor. J Med Chem50:2903-15 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50213118 |
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| n/a |
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| Name | BDBM50213118 |
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| Synonyms: | (S,S)-(+)-5-{2-[2-(4-aminophenyl)-1-methylethylamino]-1-hydroxyethyl}-1,3-benzenediol | CHEMBL229390 | US10617654, Compound (S,S)-3 | US9492405, (S,S)-3 | US9492405, 12 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO3 |
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| Mol. Mass. | 287.3535 |
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| SMILES | C[C@@H](Cc1ccccc1)NC[C@@H](O)c1cc(O)cc(O)c1 |
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| Structure | 
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