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TargetCannabinoid receptor 2
LigandBDBM50213608
Substrate/Competitorn/a
Meas. Tech.ChEMBL_459064 (CHEMBL925156)
Ki 63.3±n/a nM
Citation Durdagi, SKapou, AKourouli, TAndreou, TNikas, SPNahmias, VRPapahatjis, DPPapadopoulos, MGMavromoustakos, T The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the C1' position of the alkyl side chain on the structural requirements for binding to cannabinoid receptors CB1 and CB2. J Med Chem50:2875-85 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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  Blast E-value cutoff:
BDBM50213608
n/a
NameBDBM50213608
Synonyms:5-(2,2-dibromo-1-hexyl-cyclopropyl)-2-((R)-6-isopropenyl-3-methyl-cyclohex-2-enyl)-benzene-1,3-diol | 5-(2,2-dibromo-1-hexylcyclopropyl)-2-((1R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-enyl)benzene-1,3-diol | CHEMBL394006
TypeSmall organic molecule
Emp. Form.C25H34Br2O2
Mol. Mass.526.344
SMILESCCCCCCC1(CC1(Br)Br)c1cc(O)c([C@@H]2C=C(C)CCC2C(C)=C)c(O)c1 |w:22.24,6.5,t:18|
Structure
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