| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50213621 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_456157 (CHEMBL888169) |
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| Ki | 1360±n/a nM |
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| Citation |  Kai, H; Morioka, Y; Murashi, T; Morita, K; Shinonome, S; Nakazato, H; Kawamoto, K; Hanasaki, K; Takahashi, F; Mihara, S; Arai, T; Abe, K; Okabe, H; Baba, T; Yoshikawa, T; Takenaka, H 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: discovery of CB2 receptor selective compounds. Bioorg Med Chem Lett17:4030-4 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50213621 |
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| n/a |
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| Name | BDBM50213621 |
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| Synonyms: | (Z)-N-(3-benzyl-5,5-dimethyl-1,3-thiazinan-2-ylidene)-2-isopropylbenzenamine | CHEMBL247543 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N2S |
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| Mol. Mass. | 352.536 |
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| SMILES | CC(C)c1ccccc1\N=C1/SCC(C)(C)CN1Cc1ccccc1 |
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| Structure | 
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