| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
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| Ligand | BDBM50131739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_437001 (CHEMBL886017) |
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| EC50 | 2600±n/a nM |
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| Citation |  Kasuga, J; Nakagome, I; Aoyama, A; Sako, K; Ishizawa, M; Ogura, M; Makishima, M; Hirono, S; Hashimoto, Y; Miyachi, H Design, synthesis, and evaluation of potent, structurally novel peroxisome proliferator-activated receptor (PPAR) delta-selective agonists. Bioorg Med Chem15:5177-90 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor gamma |
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| Name: | Peroxisome proliferator-activated receptor gamma |
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| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
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| Type: | Nuclear Receptor |
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| Mol. Mass.: | 57613.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37231 |
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| Residue: | 505 |
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| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
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| BDBM50131739 |
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| n/a |
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| Name | BDBM50131739 |
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| Synonyms: | (+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamido)methyl)benzyl)butanoic acid | 2-(4-methoxy-3-((4-(trifluoromethyl)benzamido)methyl)benzyl)butanoic acid | 2-{4-Methoxy-3-[(4-trifluoromethyl-benzoylamino)-methyl]-benzyl}-butyric acid | 2-{4-methoxy-3-[(4-trifluoromethylbenzoylamino)-methyl]phenylmethyl}butyric acid | CHEMBL118939 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22F3NO4 |
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| Mol. Mass. | 409.3989 |
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| SMILES | CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O |
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| Structure | 
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