| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Motilin receptor |
|---|
| Ligand | BDBM50214263 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_447562 (CHEMBL896576) |
|---|
| Ki | 100±n/a nM |
|---|
| Citation |  Marsault, E; Benakli, K; Beaubien, S; Saint-Louis, C; Déziel, R; Fraser, G Potent macrocyclic antagonists to the motilin receptor presenting novel unnatural amino acids. Bioorg Med Chem Lett17:4187-90 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Motilin receptor |
|---|
| Name: | Motilin receptor |
|---|
| Synonyms: | G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45365.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_122664 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
|
|
|
|---|
| BDBM50214263 |
|---|
| n/a |
|---|
| Name | BDBM50214263 |
|---|
| Synonyms: | 1-{[(5R,8R,11S)-5-[(3-chlorophenyl)methyl]-6,9,12-trioxo-8-(propan-2-yl)-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-1,4,7,10,13-benzoxatetrazacyclooctadecin-11-yl]methyl}-2-cyanoguanidine | CHEMBL411408 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H39ClN8O4 |
|---|
| Mol. Mass. | 611.135 |
|---|
| SMILES | CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)[C@H](CN=C(N)NC#N)NC1=O |w:34.35| |
|---|
| Structure | 
|
|---|
Search and Browse
