| Reaction Details |
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 | Report a problem with these data |
| Target | Motilin receptor |
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| Ligand | BDBM50199378 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_447562 (CHEMBL896576) |
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| Ki | 664±n/a nM |
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| Citation |  Marsault, E; Benakli, K; Beaubien, S; Saint-Louis, C; Déziel, R; Fraser, G Potent macrocyclic antagonists to the motilin receptor presenting novel unnatural amino acids. Bioorg Med Chem Lett17:4187-90 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Motilin receptor |
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| Name: | Motilin receptor |
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| Synonyms: | G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45365.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_122664 |
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| Residue: | 412 |
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| Sequence: | MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTV
MLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEG
CTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVE
QDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPA
QLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVL
LVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISK
KYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
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| BDBM50199378 |
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| n/a |
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| Name | BDBM50199378 |
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| Synonyms: | (9R,12R,15S)-15-(4-amino-butyl)-9-(4-hydroxy-benzyl)-12-isopropyl-6,7,8,9,11,12,14,15,17,18-decahydro-5-oxa-8,11,14,17-tetraaza-benzocyclooctadecene-10,13,16-trione | CHEMBL214508 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H43N5O5 |
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| Mol. Mass. | 565.7036 |
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| SMILES | CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2\C=C\CNC(=O)[C@H](CCCCN)NC1=O |t:28| |
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| Structure | 
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