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TargetMelanocortin receptor 4
LigandBDBM50215813
Substrate/Competitorn/a
Meas. Tech.ChEMBL_447747
Ki 2.1±n/a nM
Citation Poitout LBrault VSackur CBernetière SCamara JPlas PRoubert P Identification of a novel series of benzimidazoles as potent and selective antagonists of the human melanocortin-4 receptor. Bioorg Med Chem Lett 17:4464-70 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melanocortin receptor 4
Name:Melanocortin receptor 4
Synonyms:MC4-R | MC4R | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:Enzyme
Mol. Mass.:36949.50
Organism:Homo sapiens (Human)
Description:P32245
Residue:332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50215813
n/a
NameBDBM50215813
Synonyms:CHEMBL395226 | N,N-diisopentyl-2-(4-nitrophenylamino)-3-(3-(piperidin-1-yl)propyl)-3H-benzo[d]imidazole-5-carboxamide
TypeSmall organic molecule
Emp. Form.C32H46N6O3
Mol. Mass.562.746
SMILESCC(C)CCN(CCC(C)C)C(=O)c1ccc2nc(Nc3ccc(cc3)[N+]([O-])=O)n(CCCN3CCCCC3)c2c1
Structure
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