| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C delta type |
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| Ligand | BDBM50216860 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_440176 (CHEMBL890490) |
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| Ki | 2.13±n/a nM |
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| Citation |  Choi, Y; Pu, Y; Peach, ML; Kang, JH; Lewin, NE; Sigano, DM; Garfield, SH; Blumberg, PM; Marquez, VE Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta. J Med Chem50:3465-81 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C delta type |
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| Name: | Protein kinase C delta type |
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| Synonyms: | KPCD_MOUSE | Pkcd | Prkcd | Protein kinase C delta | Protein kinase C delta type | nPKC-delta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 77554.99 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1351519 |
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| Residue: | 674 |
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| Sequence: | MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKTTFD
AHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQY
FLEDGDCKQSMRSEEEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSR
KLDTTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGSTRCTLENFTFQKVLGKGSFGK
VLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWESPFLTHLICTFQTKDH
LFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLD
RDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEML
IGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPF
FKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHG
FSFVNPKFEQFLDI
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| BDBM50216860 |
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| n/a |
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| Name | BDBM50216860 |
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| Synonyms: | CHEMBL230048 | Z-[2-(Hydroxymethyl)-4-(3-methylbutylidene)-5-oxo-2-(2,3-dihydrofuryl)]methyl 5-Methyl-3-(2-methylpropyl)hexanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C22H38O5 |
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| Mol. Mass. | 382.5341 |
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| SMILES | CC(C)C\C=C1\CC(CO)(COC(=O)CC(CC(C)C)CC(C)C)OC1=O |w:7.9| |
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| Structure | 
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