| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
|---|
| Ligand | BDBM50029051 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_444831 (CHEMBL895082) |
|---|
| EC50 | 794±n/a nM |
|---|
| Citation |  Crassous, PA; Cardinaletti, C; Carrieri, A; Bruni, B; Di Vaira, M; Gentili, F; Ghelfi, F; Giannella, M; Paris, H; Piergentili, A; Quaglia, W; Schaak, S; Vesprini, C; Pigini, M Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist. J Med Chem50:3964-8 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-2C adrenergic receptor |
|---|
| Name: | Alpha-2C adrenergic receptor |
|---|
| Synonyms: | ADA2C_HUMAN | ADRA2C | ADRA2L2 | ADRA2RL2 | Adrenergic alpha2C | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2C-, receptor | Alpha-2 adrenergic receptor subtype C4 | Alpha-2C adrenoceptor | Alpha-2C adrenoreceptor | adrenergic, alpha-2C-, receptor [Homo sapiens] |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49552.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P18825 |
|---|
| Residue: | 462 |
|---|
| Sequence: | MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
|
|
|
|---|
| BDBM50029051 |
|---|
| n/a |
|---|
| Name | BDBM50029051 |
|---|
| Synonyms: | (-)-arterenol | (-)-noradrenaline | (-)-norepinephrine | (R)-(-)-norepinephrine | (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol | (R)-noradrenaline | (R)-norepinephrine | 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | CHEMBL1437 | NOREPINEPHRINE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H11NO3 |
|---|
| Mol. Mass. | 169.1778 |
|---|
| SMILES | NC[C@H](O)c1ccc(O)c(O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
