| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50219059 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_445303 (CHEMBL894444) |
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| Ki | 1000±n/a nM |
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| Citation |  Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits. J Med Chem50:3883-90 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50219059 |
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| n/a |
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| Name | BDBM50219059 |
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| Synonyms: | CHEMBL390212 | N-(3-{1-[3-(4-methoxyphenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide |
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| Type | Small organic molecule |
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| Emp. Form. | C29H34N2O3 |
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| Mol. Mass. | 458.5919 |
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| SMILES | COc1ccc(Oc2cccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)c2)cc1 |
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| Structure | 
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