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TargetMu-type opioid receptor
LigandBDBM50219925
Substrate/Competitorn/a
Meas. Tech.ChEMBL_449060 (CHEMBL899318)
Ki 7.4±n/a nM
Citation Takeuchi, KHolloway, WGMcKinzie, JHSuter, TMStatnick, MASurface, PLEmmerson, PJThomas, EMSiegel, MGMatt, JEWolfe, CNMitch, CH Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1. Bioorg Med Chem Lett17:5349-52 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50219925
n/a
NameBDBM50219925
Synonyms:6-(4-(2-(benzylamino)ethyl)phenoxy)nicotinamide | CHEMBL237066
TypeSmall organic molecule
Emp. Form.C21H21N3O2
Mol. Mass.347.4103
SMILESNC(=O)c1ccc(Oc2ccc(CCNCc3ccccc3)cc2)nc1
Structure
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