| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 7 |
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| Ligand | BDBM50174527 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_445956 (CHEMBL896249) |
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| EC50 | >500000±n/a nM |
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| Citation |  Selvam, C; Goudet, C; Oueslati, N; Pin, JP; Acher, FC L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency. J Med Chem50:4656-64 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 7 |
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| Name: | Metabotropic glutamate receptor 7 |
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| Synonyms: | GRM7_RAT | Gprc1g | Grm7 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 7 (mGlu7) | Mglur7 | mGlu7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 102244.48 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P35400 |
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| Residue: | 915 |
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| Sequence: | MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK
GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL
TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA
STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ
ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK
RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR
NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH
ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIF
QYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTP
CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAML
GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV
FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW
FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV
PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML
YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNS
PAAKKKYVSYNNLVI
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| BDBM50174527 |
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| n/a |
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| Name | BDBM50174527 |
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| Synonyms: | (S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric acid; hydrochloride | CHEMBL145114 | CHEMBL535153 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H12NO4P |
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| Mol. Mass. | 181.1268 |
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| SMILES | CP(O)(=O)CC[C@H](N)C(O)=O |
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| Structure | 
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