Ki Summary

Reaction Details

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Target

Phospholipase A2

Ligand

BDBM50129952

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_457563 (CHEMBL922763)

IC50

>100000±n/a nM

Citation

Moon, TC; Quan, Z; Kim, J; Kim, HP; Kudo, I; Murakami, M; Park, H; Chang, HW Inhibitory effect of synthetic C-C biflavones on various phospholipase A(2)s activity. Bioorg Med Chem15:7138-43 (2007) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Phospholipase A2

Name:

Phospholipase A2

Synonyms:

PA21B_RAT | Phospholipase A2 group 1B | Pla2g1b

Type:

PROTEIN

Mol. Mass.:

16427.59

Organism:

Rattus norvegicus

Description:

ChEMBL_156506

Residue:

146

Sequence:

MKLLLLAALLTAGVTAHSISTRAVWQFRNMIKCTIPGSDPLREYNNYGCYCGLGGSGTPV
DDLDRCCQTHDHCYNQAKKLESCKFLIDNPYTNTYSYKCSGNVITCSDKNNDCESFICNC
DRQAAICFSKVPYNKEYKDLDTKKHC

BDBM50129952

n/a

Name

BDBM50129952

Synonyms:

2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one | 8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one | Amentoflavone | CHEMBL63354 | cid_5281600

Type

Small organic molecule

Emp. Form.

C30H18O10

Mol. Mass.

538.4579

SMILES

Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)|

Structure