| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50221424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_449624 (CHEMBL898721) |
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| Ki | 1±n/a nM |
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| Citation |  Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Design and synthesis of opioidmimetics containing 2',6'-dimethyl-L-tyrosine and a pyrazinone-ring platform. Bioorg Med Chem Lett17:5768-71 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50221424 |
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| n/a |
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| Name | BDBM50221424 |
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| Synonyms: | (S)-2-amino-N-(3-(5-benzyl-6-methyl-3-oxo-3,4-dihydropyrazin-2-yl)propyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide | CHEMBL236461 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N4O3 |
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| Mol. Mass. | 448.5573 |
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| SMILES | Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(Cc2ccccc2)[nH]c1=O |
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| Structure | 
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