| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50226008 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_458722 (CHEMBL942057) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Blagg, J; Allerton, CM; Batchelor, DV; Baxter, AD; Burring, DJ; Carr, CL; Cook, AS; Nichols, CL; Phipps, J; Sanderson, VG; Verrier, H; Wong, S Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route. Bioorg Med Chem Lett17:6691-6 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49303.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21728 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
|
|
|
|---|
| BDBM50226008 |
|---|
| n/a |
|---|
| Name | BDBM50226008 |
|---|
| Synonyms: | (R)-3-(4-propylmorpholin-2-yl)phenol | CHEMBL250403 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H19NO2 |
|---|
| Mol. Mass. | 221.2955 |
|---|
| SMILES | CCCN1CCO[C@@H](C1)c1cccc(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
