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TargetCarboxypeptidase N, catalytic subunit
LigandBDBM50226600
Substrate/Competitorn/a
Meas. Tech.ChEMBL_452078
Ki>10000±n/a nM
Citation Bunnage MEBlagg JSteele JOwen DRAllerton CMcElroy ABMiller DRinger TButcher KBeaumont KEvans KGray AJHolland SJFeeder NMoore RSBrown DG Discovery of potent& selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J Med Chem 50:6095-103 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carboxypeptidase N, catalytic subunit
Name:Carboxypeptidase N, catalytic subunit
Synonyms:Anaphylatoxin inactivator | Arginine carboxypeptidase | CPN | Carboxypeptidase N catalytic chain | Carboxypeptidase N polypeptide 1 | Carboxypeptidase N small subunit | Kininase-1 | Lysine carboxypeptidase | Plasma carboxypeptidase B | SCPN | Serum carboxypeptidase N
Type:PROTEIN
Mol. Mass.:52293.66
Organism:Homo sapiens (Human)
Description:ChEMBL_1496379
Residue:458
Sequence:
MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50226600
n/a
NameBDBM50226600
Synonyms:(2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)propanoic acid | CHEMBL235697
TypeSmall organic molecule
Emp. Form.C8H14N4O2
Mol. Mass.198.2224
SMILESNCCN[C@@H](Cc1cnc[nH]1)C(O)=O
Structure
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