| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 5 |
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| Ligand | BDBM50227132 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_452345 (CHEMBL902582) |
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| Ki | 20±n/a nM |
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| Citation |  Guba, W; Green, LG; Martin, RE; Roche, O; Kratochwil, N; Mauser, H; Bissantz, C; Christ, A; Stahl, M From astemizole to a novel hit series of small-molecule somatostatin 5 receptor antagonists via GPCR affinity profiling. J Med Chem50:6295-8 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 5 |
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| Name: | Somatostatin receptor type 5 |
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| Synonyms: | SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39218.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35346 |
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| Residue: | 364 |
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| Sequence: | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL
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| BDBM50227132 |
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| n/a |
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| Name | BDBM50227132 |
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| Synonyms: | 4-tert-butyl-N-(1-((1,4-dimethoxynaphthalen-2-yl)methyl)piperidin-4-yl)benzamide | CHEMBL400021 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N2O3 |
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| Mol. Mass. | 460.6077 |
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| SMILES | COc1cc(CN2CCC(CC2)NC(=O)c2ccc(cc2)C(C)(C)C)c(OC)c2ccccc12 |
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| Structure | 
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