| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
|---|
| Ligand | BDBM50227867 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_461636 (CHEMBL928754) |
|---|
| Ki | 33±n/a nM |
|---|
| Citation |  Watson, RJ; Allen, DR; Birch, HL; Chapman, GA; Galvin, FC; Jopling, LA; Knight, RL; Meier, D; Oliver, K; Meissner, JW; Owen, DA; Thomas, EJ; Tremayne, N; Williams, SC Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives. Bioorg Med Chem Lett18:147-51 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 3 |
|---|
| Name: | C-X-C chemokine receptor type 3 |
|---|
| Synonyms: | CXCR3_MOUSE | Cmkar3 | Cxcr3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41020.84 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_560734 |
|---|
| Residue: | 367 |
|---|
| Sequence: | MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
|
|
|
|---|
| BDBM50227867 |
|---|
| n/a |
|---|
| Name | BDBM50227867 |
|---|
| Synonyms: | 1-(1-((9-acetyl-9-aza-bicyclo[3.3.1]non-2-en-3-yl)methyl)piperidin-4-yl)-3-(3-isopropoxyphenyl)urea | CHEMBL253247 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H38N4O3 |
|---|
| Mol. Mass. | 454.6049 |
|---|
| SMILES | CC(C)Oc1cccc(NC(=O)NC2CCN(CC3=CC4CCCC(C3)N4C(C)=O)CC2)c1 |w:24.24,20.19,t:18,TLB:27:26:18.25.19:21.23.22| |
|---|
| Structure | 
|
|---|
Search and Browse
