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TargetC-X-C chemokine receptor type 3
LigandBDBM50198392
Substrate/Competitorn/a
Meas. Tech.ChEMBL_461636
Ki 400±n/a nM
Citation Watson RJAllen DRBirch HLChapman GAGalvin FCJopling LAKnight RLMeier DOliver KMeissner JWOwen DAThomas EJTremayne NWilliams SC Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives. Bioorg Med Chem Lett 18:147-51 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-X-C chemokine receptor type 3
Name:C-X-C chemokine receptor type 3
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41020.84
Organism:Mus musculus
Description:ChEMBL_560734
Residue:367
Sequence:
MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
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  Blast E-value cutoff:
BDBM50198392
n/a
NameBDBM50198392
Synonyms:1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea | CHEMBL439399
TypeSmall organic molecule
Emp. Form.C24H29F6N3O
Mol. Mass.489.497
SMILESCC1(C)[C@@H]2C[C@H]1C(CN1CCC(CC1)NC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)=CC2 |c:34|
Structure
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