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TargetC-X-C chemokine receptor type 3
LigandBDBM50227861
Substrate/Competitorn/a
Meas. Tech.ChEMBL_461636
Ki 57±n/a nM
Citation Watson RJAllen DRBirch HLChapman GAGalvin FCJopling LAKnight RLMeier DOliver KMeissner JWOwen DAThomas EJTremayne NWilliams SC Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives. Bioorg Med Chem Lett 18:147-51 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-X-C chemokine receptor type 3
Name:C-X-C chemokine receptor type 3
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41020.84
Organism:Mus musculus
Description:ChEMBL_560734
Residue:367
Sequence:
MYLEVSERQVLDASDFAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPALYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGP
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLL
FALPDFIYLSANYDQRLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
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  Blast E-value cutoff:
BDBM50227861
n/a
NameBDBM50227861
Synonyms:1-(3-fluoro-5-(trifluoromethyl)phenyl)-3-(1-((9-pivaloyl-9-aza-bicyclo[3.3.1]non-2-en-3-yl)methyl)piperidin-4-yl)urea | CHEMBL253733
TypeSmall organic molecule
Emp. Form.C27H36F4N4O2
Mol. Mass.524.594
SMILESCC(C)(C)C(=O)N1C2CCCC1C=C(CN1CCC(CC1)NC(=O)Nc1cc(F)cc(c1)C(F)(F)F)C2 |w:7.39,11.12,t:13,TLB:4:6:13.36.12:10.8.9|
Structure
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