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TargetTranslocator protein
LigandBDBM50229593
Substrate/Competitorn/a
Meas. Tech.ChEMBL_460138 (CHEMBL924980)
Ki 0.0978±n/a nM
Citation Briard, EZoghbi, SSImaizumi, MGourley, JPShetty, HUHong, JCropley, VFujita, MInnis, RBPike, VW Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo. J Med Chem51:17-30 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:Mitochondrion membrane protein
Mol. Mass.:18945.84
Organism:Rattus norvegicus (rat)
Description:Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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  Blast E-value cutoff:
BDBM50229593
n/a
NameBDBM50229593
Synonyms:CHEMBL253596 | N-acetyl-N-(2-methoxycarbonylbenzyl)-2-phenoxyaniline
TypeSmall organic molecule
Emp. Form.C23H21NO4
Mol. Mass.375.4171
SMILESCOC(=O)c1ccccc1CN(C(C)=O)c1ccccc1Oc1ccccc1
Structure
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