| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-4 |
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| Ligand | BDBM50229625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_461857 (CHEMBL927850) |
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| IC50 | 810000±n/a nM |
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| Citation |  Magesh, S; Moriya, S; Suzuki, T; Miyagi, T; Ishida, H; Kiso, M Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: selective inhibitors of lysosomal sialidase (NEU1). Bioorg Med Chem Lett18:532-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-4 |
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| Name: | Sialidase-4 |
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| Synonyms: | NEU4 | NEUR4_HUMAN | Sialidase 4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51579.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960637 |
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| Residue: | 484 |
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| Sequence: | MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGT
LAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRN
AARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYR
VDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCN
ARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGP
GSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSW
TLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYS
DLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGC
CWPS
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| BDBM50229625 |
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| n/a |
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| Name | BDBM50229625 |
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| Synonyms: | (4S,5R,6R)-5-acetamido-6-((1S,2S)-3-benzamido-1,2-dihydroxypropyl)-4-hydroxy-5,6-dihydro-4H-pyran-2-carboxylic acid | CHEMBL253682 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2O8 |
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| Mol. Mass. | 394.3759 |
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| SMILES | CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@@H](O)[C@@H](O)CNC(=O)c1ccccc1)C(O)=O |c:7| |
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| Structure | 
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