| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50234380 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_462577 (CHEMBL928503) |
|---|
| Ki | 3±n/a nM |
|---|
| Citation |  Ermann, M; Riether, D; Walker, ER; Mushi, IF; Jenkins, JE; Noya-Marino, B; Brewer, ML; Taylor, MG; Amouzegh, P; East, SP; Dymock, BW; Gemkow, MJ; Kahrs, AF; Ebneth, A; Löbbe, S; O'Shea, K; Shih, DT; Thomson, D Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity. Bioorg Med Chem Lett18:1725-9 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52868.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21554 |
|---|
| Residue: | 472 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50234380 |
|---|
| n/a |
|---|
| Name | BDBM50234380 |
|---|
| Synonyms: | CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin-1-ylsulfonyl)benzoate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H22N2O4S |
|---|
| Mol. Mass. | 410.486 |
|---|
| SMILES | Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Oc1cccc2cccnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
