| Reaction Details |
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 | Report a problem with these data |
| Target | Lactase/phlorizin hydrolase |
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| Ligand | BDBM50242071 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_548796 (CHEMBL1034287) |
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| IC50 | 4000±n/a nM |
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| Citation |  Asano, N; Kato, A; Miyauchi, M; Kizu, H; Kameda, Y; Watson, AA; Nash, RJ; Fleet, GW Nitrogen-containing furanose and pyranose analogues from Hyacinthus orientalis. J Nat Prod61:625-8 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactase/phlorizin hydrolase |
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| Name: | Lactase/phlorizin hydrolase |
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| Synonyms: | LPH_RAT | Lactase-glycosylceramidase | Lct | Lph |
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| Type: | PROTEIN |
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| Mol. Mass.: | 217253.31 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_96426 |
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| Residue: | 1928 |
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| Sequence: | MELPWTALFLSTVLLGLSCQGSDWESDRNFISAAGPLTNDLVLNLNYPPGKQGSDVVSGN
TDHLLCQQPLPSFLSQYFSSLRASQVTHYKVLLSWAQLLPTGSSKNPDQEAVQCYRQLLQ
SLKDAQLEPMVVLCHQTPPTSSAIQREGAFADLFADYATLAFQSFGDLVEIWFTFSDLEK
VIMDLPHKDLKASALQTLSNAHRRAFEIYHRKFSSQGGKLSVVLKAEDIPELLPDPALAA
LVQGSVDFLSLDLSYECQSVATLPQKLSELQNLEPKVKVFIYTLKLEDCPATGTSPSSLL
ISLLEAINKDQIQTVGFDVNAFLSCTSNSEESPSCSLTDSLALQTEQQQETAVPSSPGSA
YQRVWAAFANQSREERDAFLQDVFPEGFLWGISTGAFNVEGGWAEGGRGPSIWDHYGNLN
AAEGQATAKVASDSYHKPASDVALLRGIRAQVYKFSISWSGLFPLGQKSTPNRQGVAYYN
KLIDRLLDSHIEPMATLFHWDLPQALQEQGGWQNESVVEAFLDYAAFCFSTFGDRVKLWV
TFHEPWVMSYAGYGTGQHAPAISDPGMASFKVAHLILKAHARTWHLYDLHHRLQQQGRVG
IVLNSDLAEPLDRKSPQDLAAAERFLHFMLGWFAHPIFVDGDYPTTSAQIQHINQQCGHP
LAQLPEFTEAEKRLLKGSADFLGLSHYTSRLISKAGRQTCTSSYDNIGGFSQHVDPEWPQ
TASPWIRVVPWGIRRLLRFASMEYTKGKLPIFLAGNGMPVGEEADLFDDSVRVNYFNWYI
NEVLKAVKEDLVDVRSYIVRSLIDGYEGPLGFSQRFGLYHVNFNDSSRPRTPRKSAYLFT
SIIEKNGFSAKKVKRNPLPVRADFTSRARVTDSLPSEVPSKAKISVEKFSKQPRFERDLF
YDGRFRDDFLWGVSSSPYQIEGGWNADGKGPSIWDNFTHTPGNGVKDNATGDVACDSYHQ
LDADLNILRTLKVKSYRFSISWSRIFPTGRNSTINKQGVDYYNRLIDSLVDNNIFPMVTL
FHWDLPQALQDIGGWENPSLIELFDSYADYCFKTFGDRVKFWMTFNEPWCHVVLGYSSGI
FPPSVQEPGWLPYKVSHIVIKAHARVYHTYDEKYRSEQKGVISLSLNTHWAEPKDPGLQR
DVEAADRMLQFTMGWFAHPIFKNGDYPDVMKWTVGNRSELQHLASSRLPTFTEEEKNYVR
GTADVFCHNTYTSVFVQHSTPRLNPPSYDDDMELKLIEMNSSTGVMHQDVPWGTRRLLNW
IKEEYGNIPIYITENGQGLENPTLDDTERIFYHKTYINEALKAYKLDGVDLRGYSAWTLM
DDFEWLLGYTMRFGLYYVDFNHVSRPRTARASARYYPDLIANNGMPLAREDEFLYGEFPK
GFIWSAASASYQVEGAWRADGKGLSIWDTFSHTPLRIGNDDNGDVACDSYHKIAEDVVAL
QNLGVSHYRFSIAWSRILPDGTTKFINEAGLSYYVRFIDALLAAGITPQVTIYHWDLPQA
LQDVGGWENETIVQRFKEYADVLFQRLGDRVKFWITLNEPFVIAAQGYGTGVSAPGISFR
PGTAPYIAGHNLIKAHAEAWHLYNDVYRARQGGTISITISSDWGEPRDPTNREHVEAARS
YVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLGAGLNKSRLPEFTESEKSRIKGTFDFFG
FNHNTTVLAYNLDYPAAFSSFDADRGVASIADSSWPVSGSFWLKVTPFGFRRILNWLKEE
YNNPPIYVTENGVSRRGEPELNDTDRIYYLRSYINEALKAVHDKVDLRGYTVWSIMDNFE
WATGFAERFGVHFVNRSDPSLPRIPRASAKFYATIVRCNGFPDPAQGPHPCLQQPEDAAP
TASPVQSEVPFLGLMLGIAEAQTALYVLFALLLLGACSLAFLTYNTGRRSKQGNAQPSQH
QLSPISSF
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| BDBM50242071 |
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| n/a |
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| Name | BDBM50242071 |
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| Synonyms: | 2,5-Dideoxy-2,5-imino-D-glycero-D-manno-heptitol | 2,5-dideoxy-2,5-imino-dl-glycero-D-manno-heptitol | CHEMBL456077 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H15NO5 |
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| Mol. Mass. | 193.1977 |
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| SMILES | OCC(O)[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O |r| |
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| Structure | 
|
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