Reaction Details | |||
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Target | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ||
Ligand | BDBM50259934 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_549445 (CHEMBL1019376) | ||
IC50 | 5400±n/a nM | ||
Citation | Lee, JS; Cho, YS; Park, EJ; Kim, J; Oh, WK; Lee, HS; Ahn, JS Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba. J Nat Prod61:867-71 (1998) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | |||
Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ||
Synonyms: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 | PLCG1_RAT | Plcg1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 148532.78 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_549445 | ||
Residue: | 1290 | ||
Sequence: |
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BDBM50259934 | |||
n/a | |||
Name | BDBM50259934 | ||
Synonyms: | 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-chromen-3-yl)-2,3-dihydroxy-9-oxo-9H-xanthene-1-carboxylic acid | CHEMBL510257 | vinaxanthone | ||
Type | Small organic molecule | ||
Emp. Form. | C28H16O14 | ||
Mol. Mass. | 576.4182 | ||
SMILES | CC(=O)c1cc2c(oc3cc(O)c(O)c(C(O)=O)c3c2=O)c(C(C)=O)c1-c1coc2cc(O)c(O)c(C(O)=O)c2c1=O |(20.43,6.8,;19.44,5.59,;17.89,5.83,;20.23,4.23,;21.56,5,;22.9,4.23,;22.9,2.7,;24.24,1.92,;25.57,2.7,;26.89,1.92,;28.22,2.7,;29.56,1.92,;28.22,4.23,;29.56,5,;26.89,5,;26.89,6.56,;28.24,7.35,;25.53,7.35,;25.57,4.23,;24.24,5,;24.24,6.56,;21.56,1.92,;21.56,.39,;20.23,-.38,;22.9,-.38,;20.23,2.7,;18.87,1.94,;18.85,.4,;17.49,-.34,;16.18,.44,;14.83,-.3,;13.52,.49,;12.17,-.25,;13.54,2.03,;12.22,2.82,;14.88,2.78,;14.9,4.35,;13.57,5.14,;16.27,5.1,;16.2,1.99,;17.56,2.73,;17.58,4.3,)| | ||
Structure |