| Reaction Details |
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 | Report a problem with these data |
| Target | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 |
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| Ligand | BDBM50259930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_549443 (CHEMBL1019374) |
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| IC50 | 74020±n/a nM |
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| Citation |  Lee, JS; Cho, YS; Park, EJ; Kim, J; Oh, WK; Lee, HS; Ahn, JS Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba. J Nat Prod61:867-71 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 |
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| Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 |
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| Synonyms: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 | PLCG1 | PLCG1_BOVIN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 148298.56 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_549444 |
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| Residue: | 1291 |
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| Sequence: | MAGAASPCANGCGPSAPSDAEVVHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIRGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRTSDITYGQFAQLYRSLMYSAQKTMDLPFLEASALRA
GERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSIWNSQLDEVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASG
STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
FPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAVRPEGKNNRLFVFSIS
MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFLAGGHCGYVLQPSVMRDEAFDPFDKS
SLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVW
PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEGL
ELASLLVKIDVFPAKQENGDLSPFGGASLRERSCDASGPLFHGRAREGSFEARYQQPFED
FRISQEHLADHFDGRDRRTPRRTRVNGDNRL
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| BDBM50259930 |
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| n/a |
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| Name | BDBM50259930 |
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| Synonyms: | 6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-heptade-cenyljsalicylic acid | CHEMBL470768 | Ginkgolic acid C17:1 (3) |
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| Type | Small organic molecule |
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| Emp. Form. | C24H38O3 |
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| Mol. Mass. | 374.5567 |
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| SMILES | CCCCCC\C=C/CCCCCCCCCc1cccc(O)c1C(O)=O |
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| Structure | 
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