| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50259782 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_524725 (CHEMBL980280) |
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| IC50 | 2500±n/a nM |
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| Citation |  Deng, JZ; Starck, SR; Hecht, SM DNA polymerase beta inhibitors from Baeckea gunniana. J Nat Prod62:1624-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38334.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1361926 |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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| BDBM50259782 |
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| n/a |
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| Name | BDBM50259782 |
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| Synonyms: | 3beta-hydroxyrus-18,20(30)-dien-28-oic acid | CHEMBL479472 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H46O3 |
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| Mol. Mass. | 454.6844 |
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| SMILES | CC1=C2[C@H]3CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)CC[C@]2(CCC1=C)C(O)=O |r,c:1| |
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| Structure | 
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