| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA polymerase beta |
|---|
| Ligand | BDBM23208 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_524729 (CHEMBL980284) |
|---|
| IC50 | 6500±n/a nM |
|---|
| Citation |  Ma, J; Starck, SR; Hecht, SM DNA polymerase beta inhibitors from Tetracera boiviniana. J Nat Prod62:1660-3 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA polymerase beta |
|---|
| Name: | DNA polymerase beta |
|---|
| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38334.34 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1361926 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
|
|
|
|---|
| BDBM23208 |
|---|
| n/a |
|---|
| Name | BDBM23208 |
|---|
| Synonyms: | (1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosane-5-carboxylic acid | Betulinic Acid, 24 | CHEMBL269277 | cid_64971 |
|---|
| Type | Terpene |
|---|
| Emp. Form. | C30H48O3 |
|---|
| Mol. Mass. | 456.7003 |
|---|
| SMILES | [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C |
|---|
| Structure | 
|
|---|
Search and Browse
