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TargetDNA polymerase beta
LigandBDBM50241570
Substrate/Competitorn/a
Meas. Tech.ChEMBL_525609
Ki 15000±n/a nM
Citation Deng JZStarck SRSun DASabat MHecht SM A new 7,8-euphadien-type triterpenoid from Brackenridgea nitida and Bleasdalea bleasdalei that inhibits DNA polymerase beta. J Nat Prod 63:1356-60 (2000) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:38334.34
Organism:Rattus norvegicus
Description:ChEMBL_1361926
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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  Blast E-value cutoff:
BDBM50241570
n/a
NameBDBM50241570
Synonyms:(24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | CHEMBL519411
TypeSmall organic molecule
Emp. Form.C31H50O3
Mol. Mass.470.7269
SMILESC[C@@H](CC\C=C(/C)C(O)=O)[C@]1(C)CC[C@]2(C)C3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]12C |r,t:16|
Structure
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