| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50241570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_525611 (CHEMBL972902) |
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| Ki | 82000±n/a nM |
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| Citation |  Deng, JZ; Starck, SR; Sun, DA; Sabat, M; Hecht, SM A new 7,8-euphadien-type triterpenoid from Brackenridgea nitida and Bleasdalea bleasdalei that inhibits DNA polymerase beta. J Nat Prod63:1356-60 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38334.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1361926 |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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| BDBM50241570 |
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| n/a |
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| Name | BDBM50241570 |
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| Synonyms: | (24E)-3beta-hydroxy-7,24-euphadien-26-oic acid | CHEMBL519411 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H50O3 |
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| Mol. Mass. | 470.7269 |
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| SMILES | C[C@@H](CC\C=C(/C)C(O)=O)[C@]1(C)CC[C@]2(C)C3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]12C |r,t:16| |
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| Structure | 
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