| Reaction Details |
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 | Report a problem with these data |
| Target | Type II restriction enzyme HindIII |
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| Ligand | BDBM50242374 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_509276 (CHEMBL996020) |
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| IC50 | 17000±n/a nM |
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| Citation |  Suzuki, K; Yahara, S; Maehata, K; Uyeda, M Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod64:204-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Type II restriction enzyme HindIII |
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| Name: | Type II restriction enzyme HindIII |
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| Synonyms: | T2D3_HAEIN | Type-2 restriction enzyme HindIII | hindIIIR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34955.31 |
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| Organism: | Haemophilus influenzae |
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| Description: | ChEMBL_509276 |
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| Residue: | 300 |
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| Sequence: | MKKSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPEAIKPSSTQ
EKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEFNYGLVADAKSFRLSRTAK
NQKDFKVKALSEWREDKDYAVLTAPFFQYPTTKSQIFKQSLDENVLLFSWEHLAILLQLD
LEETNIFSFEQLWNFPKKQSKKTSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEIN
FIEERSLIEKEYWKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
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| BDBM50242374 |
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| n/a |
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| Name | BDBM50242374 |
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| Synonyms: | CHEMBL505529 | topostatin |
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| Type | Small organic molecule |
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| Emp. Form. | C36H58N4O11S |
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| Mol. Mass. | 754.931 |
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| SMILES | CCCCCCCC(C)CC=C(C)C=CC(=O)C(C)CCC1OC(=O)[C@H](CC(OS(O)(=O)=O)C(N)=O)NC(=O)[C@@H](C)CNC(=O)C(=C)NC(=O)C1C |r,w:14.14,10.9| |
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| Structure | 
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