| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyribonuclease-1 |
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| Ligand | BDBM22984 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_509269 |
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| IC50 | >200000±n/a nM |
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| Citation |  Suzuki K; Yahara S; Maehata K; Uyeda M Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod 64:204-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyribonuclease-1 |
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| Name: | Deoxyribonuclease-1 |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31341.11 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1297301 |
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| Residue: | 282 |
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| Sequence: | MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQ
EVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYD
DGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKW
HLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAG
SLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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| BDBM22984 |
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| n/a |
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| Name | BDBM22984 |
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| Synonyms: | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione | Adriamycin | Adriblastina | CHEMBL53463 | Doxil | Doxorubicin |
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| Type | Antibiotic |
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| Emp. Form. | C27H29NO11 |
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| Mol. Mass. | 543.5193 |
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| SMILES | COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| |
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| Structure | 
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