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TargetDeoxyribonuclease-1
LigandBDBM22984
Substrate/Competitorn/a
Meas. Tech.ChEMBL_509269
IC50>200000±n/a nM
Citation Suzuki KYahara SMaehata KUyeda M Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod 64:204-7 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Deoxyribonuclease-1
Name:Deoxyribonuclease-1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:31341.11
Organism:Bos taurus
Description:ChEMBL_1297301
Residue:282
Sequence:
MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQ
EVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYD
DGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKW
HLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAG
SLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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  Blast E-value cutoff:
BDBM22984
n/a
NameBDBM22984
Synonyms:(8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione | Adriamycin | Adriblastina | CHEMBL53463 | Doxil | Doxorubicin
TypeAntibiotic
Emp. Form.C27H29NO11
Mol. Mass.543.5193
SMILESCOc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r|
Structure
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