| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50242090 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_550598 (CHEMBL999199) |
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| IC50 | 18600±n/a nM |
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| Citation |  Prakash Chaturvedula, VS; Hecht, SM; Gao, Z; Jones, SH; Feng, X; Kingston, DG New neolignans that inhibit DNA polymerase beta lyase. J Nat Prod67:964-7 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB |
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| Type: | Protein |
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| Mol. Mass.: | 38188.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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| BDBM50242090 |
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| n/a |
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| Name | BDBM50242090 |
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| Synonyms: | 2,4-Dimethoxy-5,6-methylenedioxy-1-(2-propenyl)benzene | CHEMBL469641 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14O4 |
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| Mol. Mass. | 222.2372 |
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| SMILES | COc1cc(OC)c(CC=C)c2OCOc12 |
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| Structure | 
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